MRI stands out as a significantly more effective modality for imaging dense breasts

A recent meta-analysis suggests that MRI emerges as the superior method for additional imaging in women with dense breast tissue. This comprehensive review involved more than 250,000 women screened for breast cancer, over half of whom exhibited dense breast tissue and negative mammography results. In a comparison among digital breast tomosynthesis, handheld US, automated breast US, and MRI scans for women with dense breasts and non-high-risk profiles, the analysis revealed MRI as the most effective in detecting cancer.

The challenge of dense breast tissue masking cancer on standard mammograms underscores the necessity for effective supplementary imaging methods. Approximately 47% of women in the United States have dense breasts, emphasizing the urgency to identify the most beneficial supplementary imaging technique for this population, according to experts involved in the analysis.

Dr. Vivianne Freitas, co-author of the study and assistant professor at the University of Toronto, highlighted the struggle radiologists face in distinguishing cancerous masses amidst dense tissue on mammograms. The study aimed to evaluate various supplementary screening tests for women with dense breasts and negative screening mammograms.

Among the 132,166 women with dense breasts and negative screenings, 541 breast cancers were initially overlooked but later detected through supplemental imaging. The analysis highlighted the markedly superior cancer detection rates of breast MRI compared to the other modalities studied, showcasing its ability to detect even the smallest lesions.

Dr. Freitas emphasized the potential for these findings to influence guidelines on supplementary screening, ensuring appropriate care and avoiding delayed diagnoses for women with dense breast tissue. While acknowledging MRI’s promise, she highlighted existing barriers such as accessibility and costs that need addressing before widespread adoption.

Moving forward, evaluating the cost-effectiveness and impact on mortality rates will be crucial in establishing breast MRI as the gold standard for imaging dense breast tissue, Dr. Freitas added.